cleaning a 50s hand-painted and sequined skirt?

Freezing can be effective for moths, but only if you drop the temperature rapidly down to zero, and keep it there for at least 72 hours. But most of the painted circle skirts are cotton, and moths primarily go after wool.
 
yes freezing doesn't really clean or freshen, but it's excellent for moths. It's always worth doing as a precaution, but as Maggie says, I don't usually bother for cotton.

Do you have a steamer? That's my usual method for freshening anything I don't want to wash, from the wrong side if the surface is fragile. But I should say I've never had a sequined hand-painted 50s skirt. I don't think it would be damaged by steam from the wrong side, but perhaps someone else can comment on that.

And then there is simply airing, hanging outside, will help.

You might like to read this article https://vintagefashionguild.org/care-and-cleaning/part-3-sorting-and-cleaning/
 
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