I've never watched it, but just reading about it gives me the willies. Our house is messy, but not filthy, and we still have a lot of sorting to do from last time we moved. But I'm making progress....
But this does remind me of my brother. My dad was a packrat, so it must run in the family! But, my brother's house is a fire trap. I worry about him. There are so many papers and books on his coffee table you can't see it. Same with his kitchen table (though mine isn't much better right now!). I mean, there's not garbage all over the place, but such clutter! When I stay with him when I go up to NY myself, I always try to clean up a bit, but he doesn't like anybody sorting through stuff or moving things around too much. So, last time I stayed there, he was away (I had gone up to visit my critically ill other brother). And I threw out empty envelopes postmarked years ago, scrap paper with scribbles on them that I bet even he couldn't decipher, general junk in his bathroom (empty toothpaste tubes, shampoo bottles, etc.), bits of tin foil and stuff in his kitchen. Like "lost" silverware that's dirty and he can't find it to wash 'cuz it's under something.... And did some cleaning, and just general straighening up. Although it didn't make a big difference that I could tell, my nephew told my niece that it looked like "Dad cleaned up." Of course, she had to tell him it was me who did it and not his father.
It's awful, but how do you tell your own brother he has a problem? His feelings get hurt when people try to encourage him to clean up and get rid of stuff..... I honestly think he's lived with it for so long he doesn't see it. But I really worry about him.